Details for gene set HALLMARK_XENOBIOTIC

Table: GSEA Results Summary

Dataset	P53_collapsed_symbols.P53.cls#MUT_versus_WT
Phenotype	P53.cls#MUT_versus_WT
Upregulated in class	WT
GeneSet	HALLMARK_XENOBIOTIC_METABOLISM
Enrichment Score (ES)	-0.2138443
Normalized Enrichment Score (NES)	-0.9528703
Nominal p-value	0.6136364
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ACP2	na	16	0.451	0.0184	No
2	DHRS1	na	20	0.443	0.0378	No
3	PTS	na	27	0.424	0.0560	No
4	PINK1	na	107	0.349	0.0636	No
5	LPIN2	na	198	0.316	0.0685	No
6	EPHA2	na	213	0.310	0.0809	No
7	CYP2E1	na	424	0.260	0.0713	No
8	CAT	na	476	0.252	0.0774	No
9	MAN1A1	na	478	0.252	0.0884	No
10	HSD17B2	na	480	0.252	0.0995	No
11	ETS2	na	518	0.247	0.1067	No
12	PMM1	na	578	0.238	0.1114	No
13	MCCC2	na	619	0.231	0.1176	No
14	FMO3	na	807	0.209	0.1081	No
15	CDA	na	960	0.196	0.1015	No
16	ADH1C	na	1065	0.187	0.0993	No
17	SLC1A5	na	1088	0.186	0.1054	No
18	HPRT1	na	1329	0.166	0.0886	No
19	DDC	na	1338	0.166	0.0952	No
20	SERPINA6	na	1363	0.165	0.1001	No
21	JUP	na	1368	0.164	0.1069	No
22	ARG2	na	1402	0.162	0.1108	No
23	BCAT1	na	1510	0.155	0.1069	No
24	REG1A	na	1542	0.152	0.1106	No
25	PTGDS	na	1571	0.150	0.1144	No
26	F10	na	1663	0.145	0.1117	No
27	ENTPD5	na	1730	0.139	0.1113	No
28	IGF1	na	1753	0.138	0.1152	No
29	CBR1	na	1823	0.134	0.1142	No
30	ACOX2	na	1827	0.133	0.1198	No
31	ACOX1	na	1897	0.128	0.1185	No
32	ADH5	na	1931	0.125	0.1208	No
33	PPARD	na	1942	0.124	0.1253	No
34	SPINT2	na	1970	0.122	0.1280	No
35	MAOA	na	2016	0.119	0.1287	No
36	ETFDH	na	2180	0.110	0.1172	No
37	DDAH2	na	2222	0.108	0.1179	No
38	SLC12A4	na	2244	0.107	0.1205	No
39	MTHFD1	na	2391	0.098	0.1102	No
40	RBP4	na	2462	0.094	0.1073	No
41	ITIH1	na	2478	0.093	0.1100	No
42	CYP4F2	na	2489	0.093	0.1131	No
43	CASP6	na	2667	0.084	0.0990	No
44	CA2	na	2713	0.081	0.0981	No
45	GNMT	na	2765	0.078	0.0964	No
46	COMT	na	2852	0.073	0.0910	No
47	SLC6A6	na	2908	0.071	0.0886	No
48	TGFB2	na	2931	0.069	0.0895	No
49	PTGES	na	2972	0.067	0.0885	No
50	CYP2C18	na	3188	0.057	0.0694	No
51	CYP1A1	na	3220	0.055	0.0687	No
52	GART	na	3257	0.054	0.0675	No
53	ALAS1	na	3312	0.050	0.0643	No
54	GSS	na	3350	0.048	0.0627	No
55	GSTT2	na	3480	0.042	0.0516	No
56	SLC35B1	na	3563	0.038	0.0450	No
57	SERPINE1	na	3565	0.038	0.0466	No
58	PC	na	3678	0.033	0.0368	No
59	GCLC	na	3691	0.033	0.0371	No
60	CYP26A1	na	3760	0.029	0.0315	No
61	FABP1	na	3766	0.029	0.0323	No
62	IGFBP4	na	3884	0.024	0.0216	No
63	TDO2	na	3950	0.021	0.0159	No
64	KARS	na	4064	0.014	0.0052	No
65	MBL2	na	4091	0.013	0.0032	No
66	NQO1	na	4129	0.011	-0.0000	No
67	PLG	na	4280	0.005	-0.0149	No
68	IGFBP1	na	4421	-0.002	-0.0289	No
69	G6PC	na	4460	-0.003	-0.0326	No
70	ENPEP	na	4514	-0.006	-0.0377	No
71	LCAT	na	4677	-0.013	-0.0534	No
72	PYCR1	na	4766	-0.017	-0.0615	No
73	ABCD2	na	4820	-0.020	-0.0659	No
74	ACOX3	na	4852	-0.021	-0.0681	No
75	GCH1	na	4920	-0.023	-0.0739	No
76	CROT	na	4958	-0.025	-0.0765	No
77	CDO1	na	4959	-0.025	-0.0754	No
78	GABARAPL1	na	5018	-0.027	-0.0800	No
79	ELOVL5	na	5075	-0.029	-0.0843	No
80	ALDH9A1	na	5160	-0.033	-0.0913	No
81	PGRMC1	na	5215	-0.036	-0.0951	No
82	GCNT2	na	5424	-0.045	-0.1140	No
83	PSMB10	na	5462	-0.047	-0.1156	No
84	ACO2	na	5505	-0.049	-0.1177	No
85	NMT1	na	5525	-0.050	-0.1174	No
86	FBLN1	na	5540	-0.050	-0.1166	No
87	ABCC3	na	5590	-0.053	-0.1192	No
88	ALDH2	na	5617	-0.054	-0.1194	No
89	GAD1	na	5739	-0.059	-0.1290	No
90	PGD	na	5790	-0.061	-0.1313	No
91	ADH7	na	5838	-0.063	-0.1333	No
92	ID2	na	5868	-0.064	-0.1333	No
93	VTN	na	5986	-0.069	-0.1420	No
94	CRP	na	5990	-0.069	-0.1393	No
95	HSD11B1	na	6030	-0.071	-0.1400	No
96	EPHX1	na	6093	-0.074	-0.1430	No
97	XDH	na	6142	-0.076	-0.1444	No
98	ALDH3A1	na	6255	-0.082	-0.1521	No
99	AQP9	na	6352	-0.086	-0.1579	No
100	TNFRSF1A	na	6380	-0.087	-0.1568	No
101	CYP2J2	na	6439	-0.090	-0.1586	No
102	ASL	na	6571	-0.096	-0.1675	No
103	PAPSS2	na	6605	-0.098	-0.1665	No
104	ACP1	na	6645	-0.100	-0.1660	No
105	SLC35D1	na	6668	-0.101	-0.1637	No
106	BLVRB	na	6694	-0.102	-0.1617	No
107	ECH1	na	6914	-0.112	-0.1787	No
108	DHRS7	na	6945	-0.114	-0.1767	No
109	TPST1	na	6995	-0.116	-0.1765	No
110	ATP2A2	na	7018	-0.117	-0.1735	No
111	IDH1	na	7019	-0.117	-0.1683	No
112	FETUB	na	7048	-0.119	-0.1658	No
113	PROS1	na	7450	-0.138	-0.2000	No
114	FAH	na	7453	-0.138	-0.1940	No
115	FBP1	na	7527	-0.143	-0.1950	No
116	SHMT2	na	7715	-0.152	-0.2071	Yes
117	AHCY	na	7744	-0.154	-0.2031	Yes
118	SMOX	na	7781	-0.156	-0.1998	Yes
119	F11	na	7887	-0.162	-0.2031	Yes
120	PEMT	na	7893	-0.162	-0.1964	Yes
121	HMOX1	na	7988	-0.168	-0.1984	Yes
122	DDT	na	8010	-0.169	-0.1930	Yes
123	GCKR	na	8066	-0.173	-0.1908	Yes
124	HGFAC	na	8174	-0.179	-0.1936	Yes
125	IL1R1	na	8178	-0.179	-0.1860	Yes
126	DHPS	na	8256	-0.184	-0.1856	Yes
127	BPHL	na	8283	-0.185	-0.1799	Yes
128	PDK4	na	8288	-0.186	-0.1721	Yes
129	CES1	na	8302	-0.187	-0.1651	Yes
130	HRG	na	8327	-0.188	-0.1591	Yes
131	VNN1	na	8344	-0.190	-0.1523	Yes
132	UGDH	na	8480	-0.198	-0.1571	Yes
133	ITIH4	na	8674	-0.212	-0.1671	Yes
134	GSR	na	8761	-0.217	-0.1661	Yes
135	CYP1A2	na	8768	-0.218	-0.1570	Yes
136	FMO1	na	8777	-0.218	-0.1481	Yes
137	SLC22A1	na	8808	-0.220	-0.1414	Yes
138	MPP2	na	8816	-0.221	-0.1323	Yes
139	POR	na	8848	-0.223	-0.1255	Yes
140	AKR1C3	na	8884	-0.226	-0.1190	Yes
141	NPC1	na	8976	-0.232	-0.1179	Yes
142	GSTO1	na	8982	-0.232	-0.1080	Yes
143	CYP17A1	na	9113	-0.242	-0.1104	Yes
144	TTPA	na	9146	-0.244	-0.1027	Yes
145	HNF4A	na	9299	-0.259	-0.1065	Yes
146	APOE	na	9332	-0.263	-0.0981	Yes
147	ESR1	na	9370	-0.267	-0.0899	Yes
148	ARG1	na	9541	-0.289	-0.0942	Yes
149	CYFIP2	na	9550	-0.290	-0.0821	Yes
150	TYR	na	9572	-0.293	-0.0712	Yes
151	CCL25	na	9591	-0.296	-0.0599	Yes
152	NINJ1	na	9649	-0.306	-0.0520	Yes
153	KYNU	na	9704	-0.315	-0.0435	Yes
154	CYP27A1	na	9761	-0.324	-0.0347	Yes
155	SLC6A12	na	9798	-0.331	-0.0236	Yes
156	UPP1	na	9810	-0.334	-0.0099	Yes
157	TAT	na	9957	-0.385	-0.0075	Yes
158	FAS	na	10075	-0.489	0.0024	Yes