Details for gene set HALLMARK_KRAS_SIGNALING

Table: GSEA Results Summary

Dataset	P53_collapsed_symbols.P53.cls#MUT_versus_WT
Phenotype	P53.cls#MUT_versus_WT
Upregulated in class	WT
GeneSet	HALLMARK_KRAS_SIGNALING_DN
Enrichment Score (ES)	-0.3017706
Normalized Enrichment Score (NES)	-1.1620005
Nominal p-value	0.27083334
FDR q-value	1.0
FWER p-Value	0.97

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTGFR	na	525	0.246	-0.0376	No
2	CPEB3	na	548	0.242	-0.0250	No
3	PLAG1	na	589	0.236	-0.0146	No
4	SLC38A3	na	700	0.221	-0.0122	No
5	SCGB1A1	na	827	0.207	-0.0121	No
6	FGFR3	na	965	0.196	-0.0139	No
7	KRT15	na	970	0.195	-0.0024	No
8	TNNI3	na	1189	0.177	-0.0135	No
9	TFF2	na	1218	0.175	-0.0056	No
10	ALOX12B	na	1362	0.165	-0.0099	No
11	KRT5	na	1369	0.164	-0.0005	No
12	BRDT	na	1631	0.147	-0.0177	No
13	EFHD1	na	1652	0.145	-0.0108	No
14	MYH7	na	1677	0.143	-0.0045	No
15	KRT4	na	1906	0.128	-0.0195	No
16	CALCB	na	1919	0.127	-0.0130	No
17	EPHA5	na	2113	0.113	-0.0254	No
18	RYR1	na	2144	0.112	-0.0216	No
19	CPB1	na	2163	0.111	-0.0167	No
20	SNN	na	2185	0.110	-0.0121	No
21	IGFBP2	na	2456	0.095	-0.0333	No
22	KRT13	na	2526	0.091	-0.0347	No
23	SPTBN2	na	2557	0.090	-0.0322	No
24	OXT	na	2614	0.087	-0.0325	No
25	SKIL	na	2646	0.085	-0.0305	No
26	CACNA1F	na	2671	0.083	-0.0278	No
27	CHST2	na	2676	0.083	-0.0231	No
28	LGALS7	na	2716	0.081	-0.0221	No
29	HSD11B2	na	2800	0.076	-0.0258	No
30	TSHB	na	2924	0.070	-0.0338	No
31	TGFB2	na	2931	0.069	-0.0302	No
32	CYP11B2	na	3006	0.066	-0.0336	No
33	HTR1D	na	3213	0.056	-0.0509	No
34	IRS4	na	3268	0.053	-0.0530	No
35	PDK2	na	3337	0.049	-0.0569	No
36	PROP1	na	3388	0.046	-0.0590	No
37	TFAP2B	na	3701	0.032	-0.0884	No
38	RGS11	na	3871	0.024	-0.1038	No
39	BARD1	na	3908	0.022	-0.1061	No
40	IDUA	na	3978	0.019	-0.1118	No
41	IL12B	na	4062	0.015	-0.1192	No
42	KCNMB1	na	4082	0.013	-0.1203	No
43	SLC12A3	na	4163	0.010	-0.1277	No
44	SHOX2	na	4370	0.001	-0.1483	No
45	TGM1	na	4401	-0.001	-0.1513	No
46	PNMT	na	4493	-0.005	-0.1601	No
47	MSH5	na	4701	-0.014	-0.1800	No
48	KLK8	na	4739	-0.016	-0.1827	No
49	PTPRJ	na	4782	-0.018	-0.1858	No
50	CDH16	na	4810	-0.019	-0.1874	No
51	SLC30A3	na	4839	-0.020	-0.1889	No
52	CACNG1	na	4881	-0.022	-0.1917	No
53	PAX4	na	4898	-0.022	-0.1919	No
54	SYNPO	na	4922	-0.023	-0.1928	No
55	NTF3	na	5059	-0.029	-0.2047	No
56	CLDN8	na	5060	-0.029	-0.2029	No
57	GP1BA	na	5216	-0.036	-0.2163	No
58	MX1	na	5317	-0.040	-0.2238	No
59	SNCB	na	5322	-0.041	-0.2218	No
60	ATP6V1B1	na	5325	-0.041	-0.2195	No
61	PKP1	na	5402	-0.044	-0.2244	No
62	NR4A2	na	5404	-0.044	-0.2218	No
63	EGF	na	5406	-0.044	-0.2192	No
64	IL5	na	5554	-0.051	-0.2308	No
65	YPEL1	na	5572	-0.052	-0.2293	No
66	BMPR1B	na	5773	-0.060	-0.2457	No
67	SLC16A7	na	5870	-0.064	-0.2515	No
68	SERPINB2	na	6040	-0.072	-0.2640	No
69	CD80	na	6099	-0.074	-0.2653	No
70	FSHB	na	6113	-0.075	-0.2621	No
71	CELSR2	na	6328	-0.085	-0.2783	No
72	DCC	na	6370	-0.086	-0.2772	No
73	CLPS	na	6381	-0.087	-0.2728	No
74	CLSTN3	na	6438	-0.090	-0.2730	No
75	TG	na	6444	-0.090	-0.2680	No
76	ABCB11	na	6493	-0.092	-0.2671	No
77	LFNG	na	6524	-0.094	-0.2644	No
78	PDE6B	na	6586	-0.097	-0.2646	No
79	PRODH	na	6764	-0.106	-0.2759	No
80	COL2A1	na	6801	-0.107	-0.2730	No
81	C5	na	6852	-0.109	-0.2713	No
82	KCND1	na	6946	-0.114	-0.2737	No
83	GPR3	na	7227	-0.127	-0.2940	Yes
84	KCNQ2	na	7246	-0.128	-0.2880	Yes
85	ATP4A	na	7299	-0.131	-0.2853	Yes
86	MAST3	na	7328	-0.132	-0.2800	Yes
87	KLK7	na	7377	-0.134	-0.2766	Yes
88	DTNB	na	7405	-0.136	-0.2710	Yes
89	UGT2B17	na	7501	-0.141	-0.2720	Yes
90	RIBC2	na	7578	-0.146	-0.2707	Yes
91	THRB	na	7770	-0.155	-0.2803	Yes
92	CKM	na	7776	-0.156	-0.2713	Yes
93	SSTR4	na	7791	-0.157	-0.2631	Yes
94	SLC6A3	na	7914	-0.163	-0.2654	Yes
95	PAX3	na	7940	-0.165	-0.2578	Yes
96	NOS1	na	8004	-0.169	-0.2538	Yes
97	ADRA2C	na	8131	-0.177	-0.2556	Yes
98	SPHK2	na	8140	-0.177	-0.2456	Yes
99	ARHGDIG	na	8330	-0.188	-0.2531	Yes
100	IFNG	na	8358	-0.191	-0.2441	Yes
101	NPHS1	na	8387	-0.192	-0.2352	Yes
102	GAMT	na	8514	-0.200	-0.2356	Yes
103	ITIH3	na	8683	-0.212	-0.2395	Yes
104	PDCD1	na	8749	-0.216	-0.2328	Yes
105	KRT1	na	8766	-0.218	-0.2211	Yes
106	CAPN9	na	8954	-0.230	-0.2258	Yes
107	CCNA1	na	9000	-0.233	-0.2161	Yes
108	KCNN1	na	9104	-0.241	-0.2116	Yes
109	CNTFR	na	9105	-0.242	-0.1969	Yes
110	SOX10	na	9123	-0.243	-0.1838	Yes
111	SLC5A5	na	9137	-0.243	-0.1702	Yes
112	RYR2	na	9261	-0.255	-0.1670	Yes
113	TCL1A	na	9328	-0.262	-0.1576	Yes
114	ZBTB16	na	9573	-0.293	-0.1641	Yes
115	CPA2	na	9640	-0.305	-0.1521	Yes
116	HTR1B	na	9671	-0.310	-0.1362	Yes
117	GP2	na	9693	-0.313	-0.1192	Yes
118	CCR8	na	9760	-0.324	-0.1061	Yes
119	GPR19	na	9817	-0.335	-0.0912	Yes
120	EDN2	na	9826	-0.338	-0.0714	Yes
121	MTHFR	na	9830	-0.339	-0.0510	Yes
122	TLX1	na	9837	-0.340	-0.0308	Yes
123	AKR1B10	na	9917	-0.365	-0.0165	Yes
124	BTG2	na	10090	-0.567	0.0009	Yes