Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	P53_collapsed_symbols.P53.cls#MUT_versus_WT
Phenotype	P53.cls#MUT_versus_WT
Upregulated in class	WT
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.26797524
Normalized Enrichment Score (NES)	-1.1234057
Nominal p-value	0.20512821
FDR q-value	1.0
FWER p-Value	0.98

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TNFRSF1B	na	122	0.342	0.0182	No
2	OSMR	na	319	0.285	0.0239	No
3	IL6ST	na	323	0.284	0.0488	No
4	TNFRSF21	na	496	0.250	0.0537	No
5	IFNGR1	na	777	0.212	0.0445	No
6	CD9	na	784	0.211	0.0626	No
7	IRF1	na	820	0.208	0.0776	No
8	IFNGR2	na	883	0.202	0.0893	No
9	IFNAR1	na	978	0.194	0.0971	No
10	PTPN2	na	1012	0.192	0.1108	No
11	IL3RA	na	1271	0.171	0.1002	No
12	CXCL11	na	1294	0.169	0.1130	No
13	IL15RA	na	1365	0.164	0.1206	No
14	PIM1	na	1426	0.161	0.1288	No
15	REG1A	na	1542	0.152	0.1309	No
16	PF4	na	1771	0.137	0.1202	No
17	IL6	na	2075	0.115	0.1002	No
18	TYK2	na	2093	0.114	0.1087	No
19	CSF2	na	2097	0.114	0.1185	No
20	MYD88	na	2104	0.114	0.1280	No
21	STAT3	na	2272	0.105	0.1207	No
22	TGFB1	na	2285	0.105	0.1287	No
23	CD14	na	2465	0.094	0.1192	No
24	TLR2	na	2679	0.083	0.1053	No
25	IL13RA1	na	2960	0.068	0.0834	No
26	CXCL10	na	3211	0.056	0.0634	No
27	CXCL3	na	3288	0.052	0.0604	No
28	CD44	na	3423	0.045	0.0510	No
29	STAM2	na	3549	0.039	0.0420	No
30	IL12RB1	na	3655	0.034	0.0346	No
31	BAK1	na	3725	0.031	0.0304	No
32	MAP3K8	na	4114	0.012	-0.0072	No
33	IL10RB	na	4146	0.011	-0.0093	No
34	PLA2G2A	na	4366	0.001	-0.0311	No
35	JUN	na	4816	-0.019	-0.0741	No
36	ITGB3	na	4846	-0.021	-0.0752	No
37	IL2RG	na	4952	-0.025	-0.0835	No
38	CD38	na	5041	-0.028	-0.0898	No
39	CBL	na	5153	-0.033	-0.0979	No
40	IL9R	na	5436	-0.046	-0.1220	No
41	CSF1	na	5473	-0.047	-0.1214	No
42	IL18R1	na	5577	-0.052	-0.1271	No
43	PTPN11	na	5588	-0.053	-0.1234	No
44	GRB2	na	5997	-0.070	-0.1579	No
45	CSF2RA	na	6060	-0.073	-0.1577	No
46	TNFRSF1A	na	6380	-0.087	-0.1818	No
47	IL2RA	na	6536	-0.095	-0.1888	No
48	ITGA4	na	7109	-0.122	-0.2351	No
49	ACVRL1	na	7220	-0.127	-0.2348	No
50	STAT2	na	7472	-0.139	-0.2475	No
51	CXCL9	na	7481	-0.140	-0.2360	No
52	STAT1	na	7803	-0.157	-0.2541	Yes
53	CCR1	na	7864	-0.161	-0.2458	Yes
54	LEPR	na	7950	-0.166	-0.2396	Yes
55	HMOX1	na	7988	-0.168	-0.2284	Yes
56	IL7	na	8030	-0.171	-0.2173	Yes
57	IL1R2	na	8079	-0.174	-0.2067	Yes
58	IL1R1	na	8178	-0.179	-0.2005	Yes
59	DNTT	na	8222	-0.183	-0.1887	Yes
60	PTPN1	na	8276	-0.185	-0.1776	Yes
61	ACVR1B	na	8285	-0.186	-0.1619	Yes
62	IL1B	na	8703	-0.214	-0.1846	Yes
63	IL4R	na	8721	-0.215	-0.1672	Yes
64	CCL7	na	8819	-0.221	-0.1573	Yes
65	CSF3R	na	8951	-0.230	-0.1500	Yes
66	CNTFR	na	9105	-0.242	-0.1439	Yes
67	LTB	na	9145	-0.244	-0.1261	Yes
68	SOCS1	na	9147	-0.244	-0.1046	Yes
69	CSF2RB	na	9253	-0.254	-0.0926	Yes
70	HAX1	na	9330	-0.263	-0.0769	Yes
71	CXCL13	na	9447	-0.276	-0.0640	Yes
72	CXCL1	na	9567	-0.292	-0.0499	Yes
73	SOCS3	na	9795	-0.330	-0.0433	Yes
74	TNF	na	9835	-0.340	-0.0171	Yes
75	FAS	na	10075	-0.489	0.0024	Yes