Details for gene set HALLMARK_IL2_STAT5

Table: GSEA Results Summary

Dataset	P53_collapsed_symbols.P53.cls#MUT_versus_WT
Phenotype	P53.cls#MUT_versus_WT
Upregulated in class	WT
GeneSet	HALLMARK_IL2_STAT5_SIGNALING
Enrichment Score (ES)	-0.20764275
Normalized Enrichment Score (NES)	-0.9271519
Nominal p-value	0.5483871
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	AHR	na	19	0.448	0.0197	No
2	ARL4A	na	29	0.414	0.0388	No
3	TNFRSF1B	na	122	0.342	0.0461	No
4	RABGAP1L	na	153	0.328	0.0589	No
5	ITGA6	na	340	0.279	0.0537	No
6	MAFF	na	358	0.274	0.0652	No
7	PHTF2	na	437	0.258	0.0698	No
8	TNFRSF21	na	496	0.250	0.0760	No
9	LRIG1	na	601	0.234	0.0769	No
10	COL6A1	na	618	0.232	0.0864	No
11	PRNP	na	694	0.221	0.0896	No
12	IFNGR1	na	777	0.212	0.0916	No
13	IRF6	na	801	0.209	0.0994	No
14	GPX4	na	834	0.206	0.1061	No
15	NT5E	na	864	0.203	0.1130	No
16	MUC1	na	916	0.199	0.1175	No
17	CDC6	na	931	0.198	0.1256	No
18	SLC1A5	na	1088	0.186	0.1189	No
19	HK2	na	1116	0.183	0.1250	No
20	SLC29A2	na	1261	0.172	0.1189	No
21	IL3RA	na	1271	0.171	0.1262	No
22	SERPINB6	na	1316	0.167	0.1299	No
23	RGS16	na	1331	0.166	0.1365	No
24	P4HA1	na	1376	0.163	0.1399	No
25	PIM1	na	1426	0.161	0.1428	No
26	SPRED2	na	1593	0.149	0.1333	No
27	PRAF2	na	1690	0.143	0.1305	No
28	PENK	na	1697	0.142	0.1368	No
29	GADD45B	na	1763	0.137	0.1369	No
30	TNFSF10	na	1814	0.134	0.1383	No
31	TRAF1	na	1833	0.133	0.1429	No
32	BMPR2	na	1947	0.123	0.1375	No
33	CSF2	na	2097	0.114	0.1281	No
34	MYO1C	na	2309	0.103	0.1119	No
35	TGM2	na	2366	0.100	0.1111	No
36	GATA1	na	2527	0.091	0.0994	No
37	ODC1	na	2683	0.083	0.0878	No
38	CA2	na	2713	0.081	0.0888	No
39	BCL2L1	na	2728	0.080	0.0913	No
40	CD86	na	2811	0.076	0.0867	No
41	SYT11	na	2848	0.074	0.0866	No
42	DHRS3	na	2850	0.074	0.0900	No
43	CYFIP1	na	2935	0.069	0.0849	No
44	SELP	na	2954	0.068	0.0864	No
45	PTGER2	na	3124	0.060	0.0723	No
46	CXCL10	na	3211	0.056	0.0664	No
47	CD44	na	3423	0.045	0.0474	No
48	APLP1	na	3465	0.042	0.0453	No
49	SOCS2	na	3569	0.038	0.0368	No
50	NRP1	na	3666	0.034	0.0288	No
51	TNFRSF9	na	3702	0.032	0.0268	No
52	NDRG1	na	3870	0.024	0.0112	No
53	MAP3K8	na	4114	0.012	-0.0126	No
54	CASP3	na	4286	0.004	-0.0296	No
55	ADAM19	na	4299	0.004	-0.0306	No
56	IL13	na	4361	0.001	-0.0367	No
57	HIPK2	na	4431	-0.002	-0.0435	No
58	SYNGR2	na	4495	-0.005	-0.0496	No
59	TIAM1	na	4625	-0.011	-0.0621	No
60	MYC	na	4727	-0.015	-0.0715	No
61	ITGAE	na	4781	-0.018	-0.0759	No
62	XBP1	na	4801	-0.019	-0.0769	No
63	ITGAV	na	4999	-0.026	-0.0954	No
64	RORA	na	5001	-0.026	-0.0942	No
65	GABARAPL1	na	5018	-0.027	-0.0945	No
66	RHOH	na	5177	-0.034	-0.1088	No
67	FURIN	na	5236	-0.037	-0.1128	No
68	PRKCH	na	5331	-0.041	-0.1203	No
69	CSF1	na	5473	-0.047	-0.1321	No
70	CCNE1	na	5497	-0.049	-0.1321	No
71	BMP2	na	5501	-0.049	-0.1300	No
72	IL18R1	na	5577	-0.052	-0.1351	No
73	PLSCR1	na	5626	-0.054	-0.1373	No
74	ENO3	na	5628	-0.054	-0.1347	No
75	ENPP1	na	5848	-0.063	-0.1537	No
76	FLT3LG	na	5857	-0.063	-0.1514	No
77	IL10RA	na	5988	-0.069	-0.1611	No
78	COCH	na	6092	-0.074	-0.1679	No
79	P2RX4	na	6401	-0.088	-0.1946	No
80	SERPINC1	na	6518	-0.093	-0.2017	No
81	IL2RA	na	6536	-0.095	-0.1989	No
82	IFITM3	na	6592	-0.097	-0.1997	No
83	POU2F1	na	6608	-0.098	-0.1965	No
84	IGF2R	na	6630	-0.099	-0.1938	No
85	ABCB1	na	6746	-0.105	-0.2003	No
86	PLAGL1	na	6758	-0.106	-0.1963	No
87	MYO1E	na	6872	-0.110	-0.2023	Yes
88	AGER	na	6887	-0.111	-0.1984	Yes
89	IL10	na	6888	-0.111	-0.1930	Yes
90	CCR4	na	6956	-0.114	-0.1943	Yes
91	CD83	na	6967	-0.115	-0.1897	Yes
92	NFIL3	na	6973	-0.115	-0.1847	Yes
93	IGF1R	na	6989	-0.116	-0.1806	Yes
94	UMPS	na	7007	-0.117	-0.1766	Yes
95	LIF	na	7032	-0.118	-0.1733	Yes
96	ETV4	na	7036	-0.118	-0.1679	Yes
97	PHLDA1	na	7045	-0.119	-0.1630	Yes
98	CDKN1C	na	7069	-0.120	-0.1595	Yes
99	UCK2	na	7132	-0.123	-0.1598	Yes
100	IL1RL1	na	7286	-0.130	-0.1689	Yes
101	CKAP4	na	7317	-0.132	-0.1655	Yes
102	SLC2A3	na	7357	-0.133	-0.1630	Yes
103	EMP1	na	7394	-0.135	-0.1601	Yes
104	FAH	na	7453	-0.138	-0.1593	Yes
105	RRAGD	na	7521	-0.142	-0.1591	Yes
106	CD81	na	7583	-0.146	-0.1582	Yes
107	ANXA4	na	7618	-0.147	-0.1545	Yes
108	AHCY	na	7744	-0.154	-0.1597	Yes
109	SELL	na	7763	-0.155	-0.1540	Yes
110	BATF	na	7782	-0.156	-0.1483	Yes
111	CCND3	na	7924	-0.164	-0.1545	Yes
112	SLC39A8	na	7927	-0.164	-0.1468	Yes
113	RHOB	na	7981	-0.168	-0.1440	Yes
114	CST7	na	8017	-0.170	-0.1393	Yes
115	NCOA3	na	8035	-0.172	-0.1327	Yes
116	IL1R2	na	8079	-0.174	-0.1287	Yes
117	TNFSF11	na	8090	-0.174	-0.1213	Yes
118	CD48	na	8165	-0.179	-0.1201	Yes
119	CD79B	na	8168	-0.179	-0.1116	Yes
120	FGL2	na	8171	-0.179	-0.1032	Yes
121	CCND2	na	8250	-0.184	-0.1022	Yes
122	CAPG	na	8445	-0.196	-0.1122	Yes
123	ECM1	na	8632	-0.209	-0.1208	Yes
124	IL4R	na	8721	-0.215	-0.1193	Yes
125	SPP1	na	8788	-0.219	-0.1153	Yes
126	TNFRSF8	na	8897	-0.226	-0.1153	Yes
127	CAPN3	na	8926	-0.228	-0.1071	Yes
128	GSTO1	na	8982	-0.232	-0.1014	Yes
129	SCN9A	na	9024	-0.235	-0.0942	Yes
130	IL2RB	na	9109	-0.242	-0.0910	Yes
131	LTB	na	9145	-0.244	-0.0827	Yes
132	SOCS1	na	9147	-0.244	-0.0710	Yes
133	CTSZ	na	9224	-0.251	-0.0665	Yes
134	ICOS	na	9281	-0.257	-0.0598	Yes
135	IRF4	na	9485	-0.282	-0.0665	Yes
136	MAPKAPK2	na	9486	-0.282	-0.0529	Yes
137	AMACR	na	9487	-0.283	-0.0393	Yes
138	TNFRSF4	na	9578	-0.294	-0.0341	Yes
139	GPR65	na	9686	-0.312	-0.0298	Yes
140	SMPDL3A	na	9732	-0.319	-0.0189	Yes
141	S100A1	na	9776	-0.326	-0.0075	Yes
142	F2RL2	na	10006	-0.404	-0.0110	Yes
143	BCL2	na	10028	-0.420	0.0071	Yes