| Dataset | P53_collapsed_symbols.P53.cls#MUT_versus_WT |
| Phenotype | P53.cls#MUT_versus_WT |
| Upregulated in class | WT |
| GeneSet | HALLMARK_APOPTOSIS |
| Enrichment Score (ES) | -0.21004209 |
| Normalized Enrichment Score (NES) | -1.0062143 |
| Nominal p-value | 0.5 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PPP2R5B | na | 67 | 0.372 | 0.0105 | No | ||
| 2 | DAP | na | 75 | 0.369 | 0.0269 | No | ||
| 3 | BCL10 | na | 188 | 0.320 | 0.0305 | No | ||
| 4 | RELA | na | 195 | 0.317 | 0.0446 | No | ||
| 5 | DFFA | na | 243 | 0.301 | 0.0539 | No | ||
| 6 | WEE1 | na | 382 | 0.270 | 0.0526 | No | ||
| 7 | PSEN1 | na | 466 | 0.254 | 0.0560 | No | ||
| 8 | ERBB2 | na | 552 | 0.241 | 0.0587 | No | ||
| 9 | PAK1 | na | 723 | 0.218 | 0.0518 | No | ||
| 10 | IFNGR1 | na | 777 | 0.212 | 0.0563 | No | ||
| 11 | IRF1 | na | 820 | 0.208 | 0.0617 | No | ||
| 12 | GPX4 | na | 834 | 0.206 | 0.0699 | No | ||
| 13 | NEFH | na | 1002 | 0.192 | 0.0621 | No | ||
| 14 | BNIP3L | na | 1042 | 0.189 | 0.0669 | No | ||
| 15 | DNAJC3 | na | 1069 | 0.187 | 0.0730 | No | ||
| 16 | ROCK1 | na | 1076 | 0.187 | 0.0811 | No | ||
| 17 | IL18 | na | 1100 | 0.185 | 0.0873 | No | ||
| 18 | CAV1 | na | 1152 | 0.180 | 0.0906 | No | ||
| 19 | H1F0 | na | 1185 | 0.177 | 0.0956 | No | ||
| 20 | TOP2A | na | 1242 | 0.173 | 0.0980 | No | ||
| 21 | SOD2 | na | 1301 | 0.168 | 0.1000 | No | ||
| 22 | CDC25B | na | 1335 | 0.166 | 0.1044 | No | ||
| 23 | DNAJA1 | na | 1339 | 0.166 | 0.1118 | No | ||
| 24 | BID | na | 1359 | 0.165 | 0.1175 | No | ||
| 25 | PLAT | na | 1364 | 0.165 | 0.1247 | No | ||
| 26 | EBP | na | 1380 | 0.163 | 0.1308 | No | ||
| 27 | BCL2L2 | na | 1442 | 0.159 | 0.1321 | No | ||
| 28 | MMP2 | na | 1489 | 0.156 | 0.1347 | No | ||
| 29 | CASP9 | na | 1521 | 0.154 | 0.1387 | No | ||
| 30 | SMAD7 | na | 1524 | 0.153 | 0.1457 | No | ||
| 31 | GADD45A | na | 1592 | 0.149 | 0.1459 | No | ||
| 32 | CTH | na | 1603 | 0.148 | 0.1518 | No | ||
| 33 | VDAC2 | na | 1612 | 0.148 | 0.1578 | No | ||
| 34 | LMNA | na | 1724 | 0.140 | 0.1532 | No | ||
| 35 | DNM1L | na | 1746 | 0.138 | 0.1575 | No | ||
| 36 | BIK | na | 1758 | 0.138 | 0.1628 | No | ||
| 37 | GADD45B | na | 1763 | 0.137 | 0.1687 | No | ||
| 38 | TNFSF10 | na | 1814 | 0.134 | 0.1699 | No | ||
| 39 | BIRC3 | na | 1955 | 0.123 | 0.1616 | No | ||
| 40 | PTK2 | na | 1965 | 0.122 | 0.1663 | No | ||
| 41 | TGFBR3 | na | 1978 | 0.122 | 0.1708 | No | ||
| 42 | MADD | na | 2073 | 0.116 | 0.1667 | No | ||
| 43 | IL6 | na | 2075 | 0.115 | 0.1720 | No | ||
| 44 | ANXA1 | na | 2130 | 0.112 | 0.1718 | No | ||
| 45 | F2R | na | 2218 | 0.108 | 0.1680 | No | ||
| 46 | DPYD | na | 2408 | 0.098 | 0.1536 | No | ||
| 47 | SPTAN1 | na | 2441 | 0.096 | 0.1548 | No | ||
| 48 | CD14 | na | 2465 | 0.094 | 0.1569 | No | ||
| 49 | PEA15 | na | 2613 | 0.087 | 0.1462 | No | ||
| 50 | BCAP31 | na | 2640 | 0.085 | 0.1475 | No | ||
| 51 | CASP6 | na | 2667 | 0.084 | 0.1488 | No | ||
| 52 | BCL2L1 | na | 2728 | 0.080 | 0.1465 | No | ||
| 53 | APP | na | 2731 | 0.080 | 0.1500 | No | ||
| 54 | PPT1 | na | 2776 | 0.077 | 0.1492 | No | ||
| 55 | SATB1 | na | 2808 | 0.076 | 0.1496 | No | ||
| 56 | TGFB2 | na | 2931 | 0.069 | 0.1405 | No | ||
| 57 | ENO2 | na | 2975 | 0.067 | 0.1393 | No | ||
| 58 | CYLD | na | 3000 | 0.066 | 0.1400 | No | ||
| 59 | CD44 | na | 3423 | 0.045 | 0.0997 | No | ||
| 60 | SOD1 | na | 3500 | 0.041 | 0.0940 | No | ||
| 61 | HMGB2 | na | 3543 | 0.039 | 0.0915 | No | ||
| 62 | CCND1 | na | 3593 | 0.037 | 0.0883 | No | ||
| 63 | KRT18 | na | 3779 | 0.028 | 0.0711 | No | ||
| 64 | BRCA1 | na | 3802 | 0.027 | 0.0701 | No | ||
| 65 | BTG3 | na | 3906 | 0.023 | 0.0608 | No | ||
| 66 | DAP3 | na | 3923 | 0.022 | 0.0603 | No | ||
| 67 | LUM | na | 3965 | 0.020 | 0.0571 | No | ||
| 68 | HGF | na | 4013 | 0.018 | 0.0531 | No | ||
| 69 | AVPR1A | na | 4066 | 0.014 | 0.0486 | No | ||
| 70 | NEDD9 | na | 4145 | 0.011 | 0.0412 | No | ||
| 71 | FEZ1 | na | 4232 | 0.007 | 0.0329 | No | ||
| 72 | CASP3 | na | 4286 | 0.004 | 0.0278 | No | ||
| 73 | IGFBP6 | na | 4327 | 0.003 | 0.0239 | No | ||
| 74 | ERBB3 | na | 4337 | 0.002 | 0.0231 | No | ||
| 75 | MGMT | na | 4481 | -0.004 | 0.0090 | No | ||
| 76 | PDCD4 | na | 4587 | -0.009 | -0.0012 | No | ||
| 77 | F2 | na | 4751 | -0.017 | -0.0168 | No | ||
| 78 | ETF1 | na | 4759 | -0.017 | -0.0167 | No | ||
| 79 | JUN | na | 4816 | -0.019 | -0.0214 | No | ||
| 80 | GCH1 | na | 4920 | -0.023 | -0.0307 | No | ||
| 81 | DDIT3 | na | 5036 | -0.028 | -0.0409 | No | ||
| 82 | CD38 | na | 5041 | -0.028 | -0.0400 | No | ||
| 83 | GNA15 | na | 5070 | -0.029 | -0.0415 | No | ||
| 84 | PDGFRB | na | 5093 | -0.030 | -0.0423 | No | ||
| 85 | CASP7 | na | 5403 | -0.044 | -0.0713 | No | ||
| 86 | BMP2 | na | 5501 | -0.049 | -0.0787 | No | ||
| 87 | CD69 | na | 5555 | -0.051 | -0.0817 | No | ||
| 88 | IER3 | na | 5592 | -0.053 | -0.0829 | No | ||
| 89 | CREBBP | na | 5743 | -0.059 | -0.0952 | No | ||
| 90 | BCL2L11 | na | 5800 | -0.061 | -0.0980 | No | ||
| 91 | ADD1 | na | 6069 | -0.073 | -0.1215 | No | ||
| 92 | GSN | na | 6137 | -0.076 | -0.1247 | No | ||
| 93 | EREG | na | 6155 | -0.076 | -0.1229 | No | ||
| 94 | CASP1 | na | 6169 | -0.077 | -0.1206 | No | ||
| 95 | GPX1 | na | 6468 | -0.091 | -0.1463 | No | ||
| 96 | SQSTM1 | na | 6520 | -0.094 | -0.1471 | No | ||
| 97 | CASP4 | na | 6543 | -0.095 | -0.1449 | No | ||
| 98 | CLU | na | 6591 | -0.097 | -0.1451 | No | ||
| 99 | IFITM3 | na | 6592 | -0.097 | -0.1406 | No | ||
| 100 | PMAIP1 | na | 6609 | -0.098 | -0.1376 | No | ||
| 101 | IGF2R | na | 6630 | -0.099 | -0.1350 | No | ||
| 102 | TIMP1 | na | 6699 | -0.102 | -0.1371 | No | ||
| 103 | RARA | na | 6717 | -0.103 | -0.1340 | No | ||
| 104 | LEF1 | na | 6774 | -0.106 | -0.1347 | No | ||
| 105 | CDKN1B | na | 6829 | -0.108 | -0.1351 | No | ||
| 106 | ISG20 | na | 7058 | -0.120 | -0.1524 | No | ||
| 107 | CTNNB1 | na | 7080 | -0.121 | -0.1489 | No | ||
| 108 | TAP1 | na | 7117 | -0.122 | -0.1469 | No | ||
| 109 | TIMP3 | na | 7131 | -0.123 | -0.1425 | No | ||
| 110 | GPX3 | na | 7285 | -0.130 | -0.1518 | No | ||
| 111 | EMP1 | na | 7394 | -0.135 | -0.1564 | No | ||
| 112 | SLC20A1 | na | 7399 | -0.135 | -0.1505 | No | ||
| 113 | CFLAR | na | 7509 | -0.142 | -0.1549 | No | ||
| 114 | ATF3 | na | 7525 | -0.142 | -0.1498 | No | ||
| 115 | MCL1 | na | 7762 | -0.155 | -0.1663 | No | ||
| 116 | RHOB | na | 7981 | -0.168 | -0.1804 | No | ||
| 117 | HMOX1 | na | 7988 | -0.168 | -0.1732 | No | ||
| 118 | PPP3R1 | na | 8201 | -0.181 | -0.1860 | No | ||
| 119 | CCND2 | na | 8250 | -0.184 | -0.1823 | No | ||
| 120 | GUCY2D | na | 8322 | -0.188 | -0.1807 | No | ||
| 121 | TXNIP | na | 8334 | -0.189 | -0.1731 | No | ||
| 122 | IL1B | na | 8703 | -0.214 | -0.2001 | Yes | ||
| 123 | EGR3 | na | 8733 | -0.216 | -0.1930 | Yes | ||
| 124 | GSR | na | 8761 | -0.217 | -0.1856 | Yes | ||
| 125 | PRF1 | na | 8857 | -0.224 | -0.1848 | Yes | ||
| 126 | PSEN2 | na | 8981 | -0.232 | -0.1864 | Yes | ||
| 127 | CCNA1 | na | 9000 | -0.233 | -0.1774 | Yes | ||
| 128 | CASP8 | na | 9002 | -0.233 | -0.1666 | Yes | ||
| 129 | PLCB2 | na | 9008 | -0.233 | -0.1563 | Yes | ||
| 130 | CD2 | na | 9027 | -0.235 | -0.1472 | Yes | ||
| 131 | CASP2 | na | 9108 | -0.242 | -0.1440 | Yes | ||
| 132 | IFNB1 | na | 9194 | -0.249 | -0.1410 | Yes | ||
| 133 | HSPB1 | na | 9236 | -0.252 | -0.1334 | Yes | ||
| 134 | TIMP2 | na | 9794 | -0.330 | -0.1740 | Yes | ||
| 135 | TNF | na | 9835 | -0.340 | -0.1623 | Yes | ||
| 136 | CDK2 | na | 9909 | -0.362 | -0.1528 | Yes | ||
| 137 | IL1A | na | 9993 | -0.400 | -0.1426 | Yes | ||
| 138 | FAS | na | 10075 | -0.489 | -0.1280 | Yes | ||
| 139 | BTG2 | na | 10090 | -0.567 | -0.1031 | Yes | ||
| 140 | FDXR | na | 10091 | -0.568 | -0.0767 | Yes | ||
| 141 | BAX | na | 10098 | -0.823 | -0.0391 | Yes | ||
| 142 | CDKN1A | na | 10099 | -0.843 | 0.0000 | Yes |

